Stroke risk factors prepare rat brainstem tissues for modified local Shwartzman reaction.

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Stroke risk factors prepare rat brainstem tissues for modified local Shwartzman reaction.

Stroke risk factors such as hypertension, diabetes, advanced age, and genetic predisposition to stroke were demonstrated to prepare rat brainstem tissues for a modified local Shwartzman reaction. A single intracisternal injection of endotoxin provoked the reaction, and affected rats manifested neurologic deficits accompanied by pathologic lesions. Brainstem infarcts developed in only a small pr...

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Local 'Shwartzman equivalent' reaction in active chronic hepatitis

The development of a purpura-fulminans-like disorder which is a human equivalent of a local Shwartzman reaction in a woman with active chronic hepatitis is described. The cyclical appearance of blue-black, well circumscribed, haemorrhagic, acutely painful lesions in the buttocks, over the lateral aspects ofthe thighs, and on the arms suggested the diagnosis. Evidence of increased intravascular ...

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The Role of Vasoconstriction in the Local Shwartzman Reaction

The local Shwartzman reaction was provoked in the skin of the ear, hind leg, and costovertebral angle of the rabbit, as well as in the ventral abdominal skin. Certain adrenergic blocking drugs reduced the incidence of positive reactions when given prior to the provocative dose of bacterial polysaccharide. Epinephrine and other vasoconstrictor drugs administered intradermally into the prepared s...

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Prevalence of post-stroke depression and its relationship with risk factors for stroke

Background & Objective: Stroke is a major public health problem. Post-stroke depression is one of the common emotional disorders afflicting stroke survivors. The purpose of this study was to determine of the prevalence of depression and its relationship with risk factors for stroke after an episode of stroke. Materials & Methods: This descriptive study was performed on 100 consecutive patients ...

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Shwartzman reaction in germfree rabbits.

The local Shwartzman reaction occurred in germfree rabbits which had no natural antibody to endotoxin and none or only a very small amount of immunoglobulin G. From the results it was concluded that the presence of natural antibody to endotoxin is not a prerequisite of the production of the local Shwartzman reaction by bacterial endotoxin.

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ژورنال

عنوان ژورنال: Stroke

سال: 1988

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.19.7.863